INTRODUCTION:
Metabolic regulation is a crucial process that helps our bodies stay alive and healthy. It involves the chemical reactions within our cells that provide energy for various bodily functions. The energy comes from the nutrients we get from the foods we eat, such as carbohydrates, fats, and proteins. Maintaining a well-regulated metabolism is essential for survival and can help reduce the risk of certain diseases. In this article, we will explore the significance of metabolic regulation and how it relates to obesity and metabolic diseases.

METABOLISM AND ENERGY RESOURCES:
Metabolism refers to the chemical reactions that keep our cells functioning and alive. These processes require energy, which is obtained from the nutrients in the foods we eat. A healthy diet, consisting of fruits, vegetables, whole grains, and fish, provides essential nutrients and energy for our body's cells. Along with regular exercise, a balanced diet supports a well-regulated metabolism, reducing the risk of certain diseases.

THE ROLE OF METABOLIC REGULATION:
To cope with changes in energy availability, our bodies must carefully regulate metabolism. This process involves communication between different organs and tissues. After eating a meal, during exercise, or after a period of fasting, our organs need to know whether to store or mobilise energy from storage sites. Energy storage as fat is crucial for survival and allows us to adjust our energy intake as needed. However, our modern lifestyles, with sedentary habits and easy access to high-calorie foods, have contributed to the rise in overeating and obesity.

UNDERSTANDING OBESITY:
Obesity is a condition where a person's weight is elevated in relation to their height. To determine obesity, we use a measure called Body Mass Index (BMI), calculated by dividing weight in kilograms by the square of height in meters. A BMI of 30 kg/m² or more is classified as obese. While BMI is helpful, it may not consider individual variations in muscle mass. Nevertheless, most obese individuals have excess fat stores, especially in the abdomen, which can disrupt metabolic regulation.

OBESITY AND METABOLIC DISEASES:
Excess visceral fat surrounding organs can negatively impact metabolic regulation, leading to metabolic diseases like type 2 diabetes and cardiovascular issues. These diseases have become widespread globally, prompting health authorities to address the problem of obesity and its related health risks.

THE ROLE OF BIOMARKERS:
Unlike infections that show immediate symptoms, metabolic diseases develop over time without obvious signs. To assess a person's risk of metabolic diseases, medical professionals use biomarkers, which are substances indicating a person's metabolic status and overall health. By studying these biomarkers, researchers aim to gain insight into how metabolism is affected by obesity and identify new ways to prevent and treat obesity-related diseases.

DIVERSITY AMONG INDIVIDUALS WITH OBESITY:
Though obesity generally increases the risk of metabolic diseases, not all individuals with obesity face the same risk. Some have a low-risk obesity profile, showing healthier blood fat levels and better blood glucose regulation compared to high-risk obesity individuals. Lifestyle factors, such as regular physical activity, may play a role in these differences.

CONCLUSION:
Metabolic regulation is vital for our survival and overall health. Obesity can disrupt this process, leading to metabolic diseases. However, individuals with obesity are diverse, and some may have a lower risk of developing metabolic issues. Understanding the metabolic markers associated with obesity can help improve prevention and treatment strategies, leading to better health outcomes for those affected by obesity and related conditions.